-High-throughput genotoxicity screening
In vitro cardiotoxicity evaluation
-Ion channels (hERG, Nav 1-5, Ca v 1-2)
-Real-time Cell Analysis (RTCA)
-In vitro screening of differentiated cardiomyocytes induced by hiPSC
In vitro prediction of carcinogenicity
-In vitro phototoxicity evaluation
-Phototoxic red-neutral uptake assay in 3T3 cells
Evaluation of high-throughput reproductive developmental toxicity
-Whole-embryo culture in vitro
-Screening for developmental toxicity in zebrafish embryos
General toxicity screening in vivo
-Single / repeated dose toxicity exploratory test study
-Safety evaluation of the drug product
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